Sepsis, sometimes referred to as blood poisoning, is a potentially fatal condition where the body's immune system overreacts to an infection, which may result in septic shock. Essential organs are then disrupted, accompanied by a dangerous drop in blood pressure. Rapid diagnosis and treatment with antibiotics saves lives, but this is hampered by the lack of biomarkers - currently it can take up to two days to test blood samples for sepsis.
An another important factor is that symptoms of sepsis are similar to other types of Systemic Inflammatory Response Syndrome (SIRS), but only sepsis responds to antibiotics. Giving antibiotics to patients with non-sepsis SIRS could contribute to the rising problem of antibiotic resistance.
This is an extremely exciting development which has the potential to completely transform the management of this severe disease and save thousands of lives worldwide every year. These are promising early findings, and now we need to test this approach in a large clinical trial